Collacone® max

Collacone® max

Calcium phosphate collagen cone

collacone®max is a biomimetic composite material that resembles .the native human hone in its basic biphasic composition of collagen and calcium phosphate (maxresorb®granules)

نوع ماده :
کامپوزیت biometric مشابه ساختار دو فازی استخوان طبیعی انسان ،شامل کلاژن و فسفات کلسیم (گرانول های maxresorb)

خصوصیت ساختاری:
فاز کلاژنی ماده،سیگنال های بیولوژیکی جهت التیام ساکت ایجاد می کند و فاز هیدروکسی آپاتیت معدنی آن،سبب ثبات اولیه و جذب کامل ماده با سرعت کنترل شده و آرام می شود. این ماده برای پر کردن حفره ساکت طراحی شده و پیش از استفاده از آن نیازی به آبرسانی مجدد نیست،از این ماده می توان در موارد ایمپلنت گذاری فوری به عنوان یک لایه میانی محافظ و پر کننده سوراخ ساکت استفاده کرد. در صورتی که ایمپلنت گذاری با تاخیر زمانی انجام شود،این ماده می تواند به عنوان یک ماده بازسازی کننده به شکل گیری استخوان جدید کمک کند.

کاربرد های بالینی :
• نگهداری از ساکت و ریج
• ضایعات درون استخوانی
• درمان ضایعات ایمپلنت
• ضایعاتی که در اثر درمان ریشه ایجاد می شود

نقد و بررسی ها

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اولین کسی باشید که دیدگاهی می نویسد “Collacone® max”

Collacone®max is a biomimetic composite material that resembles the native human hone in its basic biphasic composition of collagen and calcium phosphate (maxresorb®granules).

While the collagenous phase provides biological signals that promote the wound healing within the socket, the mineral hydroxyapatite phase ensures primary stability and Complete resorption at a Controlled, slow resorption rate.
collacone®max is designed to fit into the void of the extraction socket and does not require rehydration before application. collacone®max may be applied both as a protective medium and temporary void filler in the extraction socket when performing an early implantation, or as a regenerative material that assists new bone formation in the case of delayed implantation.


collacone® max is a biomimetic composite material that resembles the physical and chemical properties of the mineralized human bone matrix in its composition of collagen and biphasic calcium phosphate. The collagenous phase holds the particles in place and provides biological signals that promote wound healing within the socket. Furthermore, the natural hemostatic effect of collagen helps to control bleeding. The biphasic calcium phosphate granules comprised of 60% hydroxyapatite and 40% β-tricalcium phosphate, ensure volume stability and complete resorption at a controlled rate. collacone® max maintains the socket space and provides a scaffold for bone ingrowth and new bone tissue formation. Following application the cone is slowly resorbed and replaced by new bone

Production Process and Composition

collacone® max is made of porcine collagen and hydroxyapatite (HA) / beta-tricalcium phosphate (ß-TCP), e.g., maxresorb®. The collagen extraction procedure involves multi-stage cleaning processes that effectively remove all non-collagenous proteins and antigenic components.

maxresorb® granules are produced by mixing hydroxyapatite and beta-tricalcium phosphate (60%/40%) in a ceramic slurry; this ensures an equal distribution of the two calcium phosphate phases. The collagen solution is mixed with maxresorb® granules to form a homogenous mixture that is molded into cone shape.

socket healing.bone resorption and socket preservation

Immediately after tooth extraction, the socket fills with blood and a coagulum is formed.
Within a week, invading vascular, immune- and connective tissue cells remodel the clot into granulation tissue that is successively replaced by a provisional matrix. Mineralizing processes, starting from the socket walls, lead to the formation of new, woven bone that gradually fills the socket and is eventually replaced by mature lamellar bone.
When the socket heals naturally, the bundle bone, i.e., the bone that surrounded the tooth, quickly resorbs and the socket loses its shape. Once the newly formed bone remodels into mature bone, the ridge is further reduced. The reduced ridge and collapsed soft tissue may pose aesthetic problems as well as complicate implant placement.

The principal aim of socket preservation is to reduce the loss of alveolar bone and improve the aesthetic outcome of the final prosthesis. Preserving the bone volume prevents the need for additional augmentative procedures and enables stable implant installation. collacone® max is a composite material that helps to maintains the socket space and provides a scaffold
for bone ingrowth and new bone tissue formation.

covering of the socket

To prevent migration of granules and ensure undisturbed healing a proper coverage of collacone® max is recommended. This can be achieved by repositioning the mucoperiosteal flap over the grafted site and suture it to obtain primary closure. If primary wound closure cannot be achieved completely, further mobilization of the flap (e.g. by incision through the periosteum) is needed. Alternatively, the socket can be sealed with an autologous soft tissue punch or a collagen matrix such as mucoderm® (mucoderm® punch). Open healing is possible, but may lead to insufficient regeneration/particle integration in the coronal part of the socket with loose particle encapsulated in the soft tissue.

application in the socket

Before application of collacone® max the socket should be cleaned carefully and thoroughly with a curette to remove all tissue remnants (and potential contaminants i.e. infection). It should be ensured that the socket is intact; in case of wall defects the additional use of a barrier membrane (i.e. Jason® membrane) has to be considered. Prior to use, the cone may be cut to size if required. collacone® max should be applied to the socket without compaction (no pressing), nor overfilling (collacone max should not exceed 1-2mm below bone level). The collacone® max may be applied to the surgical site in dry status, or briefly rehydrated in blood. Excessive rehydration of the cone prior to placement should be avoided.

time point of implantation

To ensure complete integration of the material it is recommended to place implants earliest at 5-6 months post-op. In case of earlier re-entry the material might not be completely integrated. The patient’s health status and the indication are amongst the most critical factors that, beside the biomaterials applied, decide the time of healing and regeneration.